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Treatment Milestones. Al real patient.
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Discussing Ph+ CML in chronic phase treatment milestones with your doctor
 

Simply put, reaching treatment milestones shows whether your therapy is working effectively. It's vital to have ongoing discussions with your doctor about your medication, how well it is working, and any side effects you may be experiencing.

It may feel difficult to get the conversation going, so here are some questions to help you get started:

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  1. How is SCEMBLIX different from other medications that treat Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase?

  2. When might I expect to see results with SCEMBLIX?

  3. What are the most serious and common side effects of SCEMBLIX?

  4. How will I know if SCEMBLIX is working?

  5. What are some treatment milestones I should know about?

  6. What are the results of my latest blood work?

For more help getting the conversation going with your doctor:

Download Doctor Discussion Guide

Responding to treatment

A decrease in the number of cells in the body with the abnormal BCR::ABL1 gene is one example of a treatment milestone. Not every patient may be able to reach this milestone during treatment.

About major molecular response (MMR):

  • Achieving MMR is an important milestone in the treatment of Ph+ CML in chronic phase

  • MMR is reached when BCR::ABL1 gene in the blood is ≤0.1% of the level measured at initial diagnosis of CML. In this case, 1 out of 1,000 cells or fewer have the BCR::ABL1 gene

How are treatment milestones measured?

Blood monitoring is an important part of managing Ph+ CML in chronic phase. Your doctor will prescribe a range of blood tests to see if you are responding to treatment. Learn more here.

What if you’re not reaching your milestones?

If you’re not responding to your medication, it’s important to be your own advocate and talk with your doctor. It may be time to have a conversation about changing treatment. You can learn more about SCEMBLIX as a treatment option after you’ve already been on another medication by clicking here.